Get to know the CPA on the packaging of Food Products and their impact on Health

Have you ever heard the term CPA? Has thought of the chemical components that inadvertently we consume? Even our pets come into consumption.

Bisphenol A or BPA with abbreviated became one of the major research topics in recent years because it is well known that BPA has estrogenic activity. Oestrogenic activity is activity resembles the activity of in vitro and/or in vivo of natural estrogen. CPA is a component of the resin contained in almost all cans good for human food or animal food (petfood). BPA is a chemical compound produced by the condensation of acetone synthesis with two equivalents of phenol. These compounds are used to produce a particular plastic packaging and epoxy resin (Beynen 2017), and is often found on food packaging and beverage cans. A survey conducted recently by Liao and Kannan Monday (2013, 2014) in the United States and China mentioned that food cans contain BPA usually with higher concentrations compared to food packaged in glass, paper or plastic (Cunha et al. 2017).

BPA is dangerous if taken as it can affect hormone regulatory process. Small amounts of BPA consumption would increase hormonal disease progression (Beynen 2017). Hormonal diseases have symptoms that are quite complex because it directly influences the physiological functions of the body or some other. This is pretty much a hormonal diseases related to disorders of endocrine glands function. The last few years, it is known that there is a relationship between some endocrine disease with exposure to BPA in humans. BPA can cause decreased ovarian response and the success of in vitro fertilization. Exposure to BPA can also lower sperm quality in men and the occurrence of changes in the female reproductive system. In children, BPA can damage the development of the nervous system. Further note that the CPA is also associated with metabolime disease such as type 2 diabetes, cardiovascular, liver function changes, obesity, albuminaria, and oxidative stress (Cunha et al. 2017). CPA is also known to negatively affect pets who eat canned food. The results of the latest studies mention that the CPA proved to be thyroid related diseases (hyperthyroidism) in cats (Beynen 2017).

CPA is considered harmful to health because there is a possible illicit compounds that migrate from the inside coating of packaging to the food product itself due to heat treatment.

Currently several companies already require suppliers of canning Tin to not use BPA in cans that their production. Consumers began to understand the dangers of BPA so that some consumers have added BPA-free specifications on products they have requested.  The European Commission has set a tolerable daily intake (TDI) for BPA i.e. 4 µ g/kg body weight (EFSA 2015), while the maximum daily amount that can be accepted by the U.S. Environmental Protection Agency are 50 µ g/kg (FDA 2008). The EU Commission also set a limit on the amount of BPA that are allowed to migrate from packaging into food, commonly known by the migration limit. The migration limit of 0.6 mg/kg (CR EU 2011).


  • Beynen a. 2017. BPA in canned petfood. Creature Companion (2017): 33-34.
  • [CR EU 2011] Commission Regulation (EU) No. 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food.
  • Cunha S, RN, Fernandes ALves JO, Casal S, Marques a. 2017. First approach to assess the bioaccessibility of bisphenol A in canned seafood. Food Chemistry 232 (2017): 501-507.
  • CEF Panel of EFSA (EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids) (2015). Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs: Executive summary. EFSA Journal, 13 (3978), 23.
  • 2008-FDA Draft assessment of bisphenol A for use in food contact applications.
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